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Annals of the Romanian Society for Cell Biology ; 25(4):11922-11934, 2021.
Article in English | Scopus | ID: covidwho-1227406

ABSTRACT

COVID 19 Pandemic has devastated the world in 2020 with more than 86 million cases and the 18 lakh deaths worldwide. Initially considered as a respiratory infection, more and more studies point towards coagulopathy as a primary mechanism of organ damage and death caused by this virus. The purpose of this study is to look for raised D-dimer level in COVID-19 patients and assess whether they correlated with severity and outcome of the disease. Study was carried out in 100 patients with COVID-19. The mean D-dimer level on admission was 1.064 mg/L. The study finds significantly higher mean D-dimer levels (p=0.0) and significantly higher number of patients with raised (≥ 0.5 mg/L) D-dimer levels (p=0.00) in Critical and Severe Groups as compared to Moderate and Mild groups of patients. There were 48 patients with normal D-dimer (<0.5 mg/L) levels out of which 3 patients died and 52 patients with raised (≥ 0.5 mg/L) D-dimer levels, out of which 18 patients died (p=0.01).There was significantly higher number of patients requiring supplemental oxygen among patients with raised D-dimer levels (p=0.00) in Moderate group. © 2021, Annals of R.S.C.B. All rights reserved.

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